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Slow Release BioActive B-Complex

Research-supported ratios of biologically active B vitamins with the sustained benefits of a slow-release formulation

As our lives become more stressful and urgent, our water-soluble B vitamins are quickly exhausted. We need them for energy production, red blood cell and neurotransmitter production, and a myriad of other processes in the body that greatly influence how we feel.

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About Slow Release BioActive B-Complex

Add to that an active lifestyle, a limited diet, pregnancy, a diagnosis of diabetes, migraines, depression, neuropathy or cardiovascular disease and the negative effects of insufficient B vitamins are compounded.

Making things more challenging is that diet does not always provide the optimal daily allowances that are needed in these situations. Plus, some individuals may lack the ability to convert and absorb specific B vitamins.

Making things more challenging is that diet does not always provide the optimal daily allowances that are needed in these situations. Plus, some individuals may lack the ability to convert and absorb specific B vitamins. 

Pure Lab’s Slow Release BioActive B-Complex is comprised of all B vitamins, including the biologically active forms of thiamine (benfotiamine), niacin (inositol hexanicotinate), riboflavin (riboflavin-5-phosphate, folate (calcium-L-5- MTHF), B6 (pyridoxal-5-phosphate) and B12 (methylcobalamin). Like a fully-charged battery instead of a partially drained one, the vitamins in our formulation are ready to perform metabolic work as soon as they get absorbed. This balanced ratio of B vitamins in their bioavailable form provides the support necessary to improve resilience against stress. 

We consider our Slow Release BioActive B-Complex a foundation product that can benefit anyone looking for improved mental and physical energy.

Because B vitamins are water-soluble, getting used up or excreted quickly, Pure Lab’s Slow Release BioActive B-Complex product was formulated to support the maintenance of blood levels over a longer period of time—about 4 to 5 hours per capsule. That’s about twice as long as standard B complex formulations. This minimizes most individuals’ daily dose to just 1 or 2 capsules. 

We recommend taking 1 capsule with food at the start of your day, and another 1 at lunch time. Doing this, what you’re going to notice is a bright yellow tint to your urine that lasts throughout the day. That’s visible proof of the slow-release effect.

Ingredients

Research

Adams JB, Kirby JK, Sorensen JC, Pollard EL, Audhya T. Evidence based recommendations for an optimal prenatal supplement for women in the US: vitamins and related nutrientsMatern Health Neonatol Perinatol. 2022;8(1):4. Published 2022 Jul 11.

Clarke, Robert et al. Low Vitamin B-12 Status and Risk of Cognitive Decline in Older Adults. Am J Clin Nutr Nov 2007, 86 (5), 1384-91.

Clase CM, Ki V, Holden RM. Water-soluble vitamins in people with low glomerular filtration rate or on dialysis: a review. Semin Dial. 2013;26(5):546-567

Huang, Peirong et al. Homocysteine and the Risk of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis. Sci Rep 2015 Jul 21, 5, 10585.

Jacobson Bensky, Merav et al. Comparison of Sublingual vs. Intramuscular Administration of Vitamin B12 for the Treatment of Patients With Vitamin B12 Deficiency. Drug Deliv Transl Res Jun 2019, 9 (3), 625-630.

Kim H, Kim G, Jang W, Kim SY, Chang N. Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment. Nutr J. 2014;13(1):118. Published 2014 Dec 17.

Li, J., Goh, C.E., Demmer, R.T. et al. Association between Serum Folate and Insulin Resistance among U.S. Nondiabetic Adults. Sci Rep 2017:7, 9187.

Lin, Ping-Ting et al. Low Pyridoxal 5'-phosphate Is Associated With Increased Risk of Coronary Artery Disease. Nutrition Nov-Dec 2006:22 (11-12), 1146-51.

Liu KW, Dai LK, Jean W. Metformin-related vitamin B12 deficiency. Age and Ageing 2006;35:200-1.

Mahdavifar B, Hosseinzadeh M, Salehi-Abargouei A, Mirzaei M, Vafa M. Dietary intake of B vitamins and their association with depression, anxiety, and stress symptoms: A cross-sectional, population-based survey. J Affect Disord. 2021;288:92-98.

Oregon State University. “OSU Study: Poor athletic performance may be linked to nutrient deficiency.” October 23, 2009. Accessed online November 24, 2022.

Yan Ji, Song Tan, Yuming Xu, Avinash Chandra, Changhe Shi, Bo Song, Jie Qin, Yuan Gao. Vitamin B supplementation, homocysteine levels, and the risk of cerebrovascular disease:A meta-analysis. Neurology Oct 2013, 81 (15) 1298-1307.

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