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Slow Release Melatonin 10 mg

A natural sleep formula providing 10 milligrams of melatonin per sustained-release capsule

Melatonin is a hormone secreted by the pineal gland upon the shift from light to darkness, making us sleepy. It suppresses the release of noradrenaline, dopamine, and cortisol. All three of these stimulating chemical messengers can interfere with a good night’s sleep. Healthy melatonin levels are instrumental in feeling refreshed upon waking; they even support the immune system.

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60 Vegetarian Capulets

About Slow Release Melatonin 10 mg

Under normal circumstances, melatonin secretion typically peaks between 1 and 3 a.m., but only IF you’re sleeping in total darkness. If this isn’t the case, then release is suppressed and the health-giving benefits of melatonin are missed. Exposure to artificial lights, particularly blue light from electronic tablets, phones, computers and TVs, and even long flights can delay the release of melatonin and wreak havoc with the circadian rhythms that tell us when to rest and when to be alert. Deficiency can even lead to appetite changes, nausea and weight gain.

Lifestyles today often include after-dinner workouts, shift work, airline travel, sedentary jobs, increased screen time and staying up later. No wonder so many of us are experiencing daytime drowsiness, poor concentration, irritability or forgetfulness. These are all symptoms associated with sleep deprivation.

Sleep cycle disruptions affect many groups of people, such as shift workers, frequent flyers, parents of young children, illness, individuals on certain medications, and anyone with chronic stress or anxiousness.

Ingredient and Dosage Information

Pure Lab’s Slow Release Melatonin provides 10 milligrams of melatonin per sustained-release capsule, for longer lasting benefits. Our Slow Release Melatonin is designed to be taken 1 hour before bedtime to provide sustained benefits throughout the sleep cycle.

Research

Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.

 

Ari Shechter, Paul Lespérance, N. M. K. Ng Ying Kin, Diane B. Boivin. Pilot Investigation of the Circadian Plasma Melatonin Rhythm across the Menstrual Cycle in a Small Group of Women with Premenstrual Dysphoric Disorder. PLoS ONE, 2012; 7 (12): e51929 

Herxheimer A1, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev. 2002;(2):CD001520. PMID 12076414

Kandil TS, Mousa AA, El-Gendy AA, Abbas AM. The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease. BMC Gastroenterol. 2010;10:7. Published 2010 Jan 18.

Liira, J; Verbeek, JH; Costa, G; Driscoll, TR; Sallinen, M; Isotalo, LK; Ruotsalainen, JH (12 August 2014). Pharmacological interventions for sleepiness and sleep disturbances caused by shift work.. The Cochrane database of systematic reviews 8: CD009776. PMID 25113164.

Lu WZ, Gwee KA, Moochhalla S, Ho KY. Melatonin improves bowel symptoms in female patients with irritable bowel syndrome: a double-blind placebo-controlled study. Aliment Pharmacol Ther. 2005;22(10):927-934.

Masi G, Fantozzi P, Villafranca A, et al. Effects of melatonin in children with attention-deficit/hyperactivity disorder with sleep disorders after methylphenidate treatment. Neuropsychiatr Dis Treat. 2019;15:663-667. Published 2019 Mar 7. 

Office of Dietary Supplements. Magnesium: Fact Sheet for Health Professionals. National Institutes of Health. Accessed April 24, 2023.

 

Peres MF, Melatonin, the pineal gland and their implications for headache disorders. Cephalalgia. 2005 Jun;25(6):403-11.

 

Pieri C, Marra M, Moroni F, Recchioni R, Marcheselli F (1994). Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci. 55 (15): PL271–6.

 

Pohanka M (2011). Alzheimer´s disease and related neurodegenerative disorders: implication and counteracting of melatonin (PDF). Journal of Applied Biomedicine 9 (4): 185–196.

 

Reiter RJ, Manchester LC, Tan DX (September 2010). Neurotoxins: free radical mechanisms and melatonin protection. Curr Neuropharmacol 8 (3): 194–210.

 

Saha L, Malhotra S, Rana S, Bhasin D, Pandhi P. A preliminary study of melatonin in irritable bowel syndrome. J Clin Gastroenterol. 2007;41(1):29-32. 

 

Srinivasan V, Pandi-Perumal SR, Cardinali DP, Poeggeler B, Hardeland R. Melatonin in Alzheimer's disease and other neurodegenerative disordersBehav Brain Funct. 2006;2:15. Published 2006 May 4. doi:10.1186/1744-9081-2-15

 

Van der Heijden KB, Smits MG, Van Someren EJ, Ridderinkhof KR, Gunning WB. Effect of melatonin on sleep, behavior, and cognition in ADHD and chronic sleep-onset insomnia. J Am Acad Child Adolesc Psychiatry. 2007;46(2):233-241. 

 

Vogler B, Rapoport AM, Tepper SJ, Role of melatonin in the pathophysiology of migraine: implications for treatment.CNS Drugs. 2006;20(5):343-50.

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