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By Andrea Bartels CNP NNCP RNT
Registered Nutritional Therapist

02 Jun 2025

Stay Strong, Live Long: Upgrade Your Supplements for Men's Longevity

Summary:

Looking to stay energized, focused, and resilient as the years go by? Start building a supplement stack that works as hard as you do. A nutritional foundation that includes key minerals can set the stage for long-term vitality, while antioxidants help keep things balanced behind the scenes. For next-level support, discover a trio that includes powerhouse botanicals that help you stay cool under pressure and ready for anything. Whether you're in the gym, at the office, or chasing after big goals, the right supplements can help you stay on top of your game—now and for years to come.

Gentlemen, staying strong, energized, and healthy well into later decades starts with daily choices, and nutrition is at the core. From maintaining muscle mass and heart health to supporting mental sharpness and vitality, balanced nutrition and good habits can make a lasting impact - - but they can be challenging to maintain 24/7. Here are some of the most useful natural nutritional and botanical supplements to support vitality into your golden years.

In This Blog

Zinc: You may not realize it, but zinc is a mineral that plays a big role in men’s health from puberty through your senior years. From supporting testosterone production and sperm quality to keeping the immune system sharp, zinc is essential for your overall vitality. Because we naturally lose zinc through sweat and daily activity, staying topped up is key—especially if you’re active or under stress. A well-absorbed chelated zinc supplement like Pure Lab’s Zinc Glycinate can help keep your levels in check and your body performing at its best.

Magnesium: When it comes to supporting men’s cardiovascular health, this powerhouse mineral supports healthy blood pressure, keeps heart rhythm steady, and supports healthy blood vessel function—all essential for a strong, resilient heart. Magnesium also plays a key role in skeletal muscle function, with muscle maintenance a key factor in men’s health and longevity. Since stress, intense exercise, and poor dietary habits can drain magnesium stores, many men fall short without realizing it. Supplementing with a high-quality, absorbable form of magnesium like magnesium glycinate can be a simple yet powerful way to protect your heart and support overall muscle function. Pure Lab’s Magnesium Glycinate Capsules are free of non-medicinal ingredients, and are available in 165 mg and 100 mg potencies. Look for our Magnesium Glycinate Powder and naturally flavoured, coloured and sweetened Magnesium Glycinate Raspberry-Lemon Powder Mix to add to your daily shake or water bottle.

Selenium: Selenium is a trace mineral with next-level benefits for men’s longevity, particularly when it comes to cancer prevention and prostate health. As a potent antioxidant, selenium helps neutralize free radicals that contribute to cellular damage and aging. Research has linked adequate selenium levels to a reduced risk of certain cancers, including prostate cancer—one of the most common cancers in men. It also supports healthy immune function and plays a role in DNA repair, both of which are critical in keeping the body resilient over time. Ensuring optimal selenium intake, such as through supplementation with Pure Lab’s Selenomethionine 200 mcg Capsules is a smart move if you’re looking to stay strong, healthy, and protected as you age.

NAC: NAC (N-acetyl-l-cysteine) is a powerful supplement that supports healthy aging by boosting key pillars of wellness: immunity, respiratory health, and liver function. As a precursor to glutathione—the body’s master antioxidant—NAC helps defend cells against oxidative stress, which accelerates aging and weakens immune defenses. It also thins mucus in the lungs, supporting clear airways and making it especially valuable for smokers or anyone exposed to environmental pollutants on the job. In the liver, NAC plays a critical detoxifying role, helping to break down toxins and support overall liver function—vital for long-term health and vitality. Whether you’re focused on aging well, maintaining lung and liver health, or giving your body an antioxidant edge, Pure Lab’s NAC 600 mg is a smart addition to a wellness routine.

DIM: Short for diindolylmethane, DIM helps balance hormone levels by promoting the healthy metabolism of estrogen—steering it down pathways that produce more favourable, less active forms. This can be especially beneficial if you’re a male dealing with low energy, belly fat, or prostate concerns – which can be symptoms of estrogen-testosterone imbalance. Additionally, DIM supports cellular health and may help reduce oxidative stress, making it a smart addition to any men’s wellness routine focused on long-term vitality and hormone health. While cruciferous vegetables like broccoli and kale are good sources of DIM’s precursor, indole-3-carbinol, its conversion into DIM can be limited if you’ve got sub-par digestion, or you’re on a medication for acid reflux. For these reasons, consider taking a stabilized, acid-resistant DIM like Pure Lab’s DIM 200 mg daily.

Botanical Back-Up

Rhodiola, ashwagandha and l-theanine form a powerful trio not just for managing daily stress, but for supporting long-term health and longevity. Pure Lab’s AdaptaPure provides consistent therapeutic levels of each ingredient in every capsule. Here’s how they work:

Rhodiola rosea is an adaptogenic herb that may give men a natural edge when it comes to endurance, stamina, and overall physical performance. Traditionally used to combat fatigue and boost resilience in cold, high-altitude climates, rhodiola helps the body adapt to all types of modern physical and mental stressors—making it a go-to for active men or those with demanding routines. Research suggests it may enhance oxygen utilization, reduce perceived exertion during exercise, and speed up recovery, all of which contribute to better stamina and staying power. Whether you’re training hard, juggling a busy schedule, or just looking to feel more energized throughout the day, a quality standardized rhodiola supplement offers a natural way to support sustained performance without the jitters that come with caffeine-containing herbs such as guarana and yerba mate.

Ashwagandha: Chronic stress is a silent accelerator of aging—impacting everything from immune strength to cardiovascular health and cognitive function. While rhodiola enhances resilience and physical stamina, it can be even more beneficial when combined with ashwagandha. This botanical, traditionally used by East Indian cultures, balances the nervous system when used regularly. It also has an additional side benefit for men: ashwagandha has been shown to increase testosterone - - the cornerstone of men’s hormonal health, muscle maintenance and sexual vitality.  

L-theanine: Many men wrestle with the idea of losing their mental sharpness as they age, and realize stress increases their risk. L-theanine is an amino acid originally discovered in green tea that holds the secret to cognitive well-being. It promotes relaxation by calming the mind, improving focus, and promoting restful states without sedation. L-theanine does all of that, yet it’s safe to take with prescription medications, while operating heavy machinery, and at any time of day or night. 

Putting It All Together: How to Build Your Plan

Start by asking yourself:

  • Are you dealing with low energy, muscle loss, or stress?
  • Is your diet consistent, or do you miss out on key nutrients?
  • Do you want to optimize testosterone, heart health, and mental clarityas you age?

Depending on how you answered the questions above, consider starting with these combos:

  • Zinc + Magnesium– foundational minerals for hormone, muscle, and heart health
  • Selenium + NAC– antioxidant defense for cellular health, prostate, lungs, and liver
  • DIM– for estrogen-testosterone balance and prostate support
  • AdaptaPure– a trio of rhodiola, ashwagandha, and L-theanine for mental sharpness, physical endurance, and stress resilience

Building a supplement routine that matches your individual needs can help you stay ahead of aging, rather than just reacting to it. Nutrients lay the foundation for long-term vitality—supporting energy, muscle function, hormone balance, heart health, and immune defense. Meanwhile, botanicals like rhodiola, ashwagandha, and L-theanine offer backup—helping you stay sharp, focused, and resilient by buffering the effects of daily stress. Start with what your body needs most, and build from there. By supporting your health today, you're investing in a stronger, more vibrant future.

Take charge of your aging journey—and fuel your future with focused, high-quality supplementation.

References

Christudoss P, Selvakumar R, Fleming JJ, Gopalakrishnan G. Zinc status of patients with benign prostatic hyperplasia and prostate carcinoma. Indian J Urol. 2011;27(1):14-18.

Government of Canada. Monograph: Ashwagandha. Natural Health Products Ingredients Database. Accessed online September 6, 2023.

Government of Canada. Monograph: Rhodiola. Natural Health Products Ingredients Database. Accessed online October 4, 2023.

Houston M. The role of magnesium in hypertension and cardiovascular disease. J Clin Hypertens (Greenwich). 2011;13(11):843-847.

Office of Dietary Supplements. Zinc: Fact Sheet for Health Professionals. National Institutes of Health. Accessed online March 30,2023.

Le, N.T., Pham, Y.TH., Le, C.TK. et al. A U-shaped association between selenium intake and cancer risk. Sci Rep 14, 21378 (2024).

Lee PH, Hong J, Jang AS. N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression. Korean J Intern Med. 2020;35(5):1229-1237.

Liguori S, Moretti A, Paoletta M, Gimigliano F, Iolascon G. Role of Magnesium in Skeletal Muscle Health and Neuromuscular Diseases: A Scoping Review. Int J Mol Sci. 2024;25(20):11220. Published 2024 Oct 18.

Lu Y, Deng B, Xu L, Liu H, Song Y, Lin F. Effects of Rhodiola Rosea Supplementation on Exercise and Sport: A Systematic Review [published correction appears in Front Nutr. 2022 Jun 20;9:928909. doi: 10.3389/fnut.2022.928909.]. Front Nutr. 2022;9:856287. Published 2022 Apr 7.

Millea PJ. N-acetylcysteine: multiple clinical applications. Am Fam Physician. 2009;80(3):265-269.

Natreon Inc. Natreon’s Sensoril ® Ashwagandha Improves Strength Training Adaptations and Recovery in Recently Published Clinical Trial”.   Cision PRWeb 17 Dec 2018.

Rosique-Esteban N, Guasch-Ferré M, Hernández-Alonso P, Salas-Salvadó J. Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies. Nutrients. 2018;10(2):168. Published 2018 Feb 1.

Sauer AK, Vela H, Vela G, Stark P, Barrera-Juarez E, Grabrucker AM. Zinc Deficiency in Men Over 50 and Its Implications in Prostate DisordersFront Oncol. 2020;10:1293. Published 2020 Aug 6.

Tinggi U. Selenium: its role as antioxidant in human health. Environ Health Prev Med. 2008;13(2):102-108.

Tucci P, Brown I, Bewick GS, Pertwee RG, Marini P. The Plant Derived 3-3'-Diindolylmethane (DIM) Behaves as CB2 Receptor Agonist in Prostate Cancer Cellular Models. Int J Mol Sci. 2023;24(4):3620. Published 2023 Feb 11.

Yang H, Seo SG, Shin SH, et al. 3,3'-Diindolylmethane suppresses high-fat diet-induced obesity through inhibiting adipogenesis of pre-adipocytes by targeting USP2 activity. Mol Nutr Food Res. 2017;61(10):10.1002/mnfr.201700119.

Yoto, A., Motoki, M., Murao, S. et al. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J Physiol Anthropol 31, 28 (2012).


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